I went to the full dose at the beginning of november 2015 and i have not had a cold since though there were plenty of coldsufferers around me coughing and sneezing at work

Update november 2016 one year no colds i take these because i like and trust the formulation but i have to be careful to take with a lot of water and remain sitting upright because they give me heartburn if i don

I dont take flu shots and i do not take any medications